Developmental Anomalies : Fordyces Granules; Etiology Clinical Features Oral Manifestations and Treatment

CLINICAL FEATURES
The sebaceous glands sometimes ectopically develop in the various intraoral sites and are known as Fordyce’s granules.
The molar area of the buccal mucosa is the most frequent site of occurrence of the Fordyce’s granules.
They appear as small yellow spots projecting from the surface of the oral mucosa.
HISTOLOGIC FEATURES
The histologic feature is normal and is the same as found on the skin.
TREATMENT
Treatment is not required.
Dr. Hamid's Tip
The letters YCES of ForDYCES granules have a lot of hidden information in them.
Y – Yellow Spots
C – Concentrated near molars
E – Ectopically erupted
S – Sebaceous Glands

Developmental Anomalies : Peutz Jheghers Syndrome; Etiology Clinical Features Oral Manifestations and Treatment

CLINICAL FEATURES
The intestinal polyposis is a disease of the intestine. The polyps can be found all over in the intestine but manifest symptomatically only in the small intestine.
The patient frequently complains of abdominal pain. The examination reveals intussusception of the intestine.
ORAL MANIFESTATIONS
The perioral skin shows numerous pigmented spots about 1-5 mm in diameters with greater concentration towards lips and gradually fading at the periphery.
The spots can similarly be concentrated at the eyes and nose also.
Intraorally buccal mucosa is most frequently affected with pigmentation while gingiva and the hard palate follow.
Previous Topic Developmental Anomalies : Cheilitis Granlomatosa
Next Topic Developmental Anomalies : Fordyces Granules

Developmental Anomalies : Cheilitis Granulomatosa; Etiology Clinical Features Oral Manifestations and Treatment

CLINICAL FEATURES
There is a diffuse, painless swelling of the lip. The adjoining soft tissues are normal but may appear erythematous sometimes.
Scaling fissuring, vesicles and pustules are less common features.
Melkersson – Rosenthal syndrome: A triad consisting of Cheilitis granulomatosa facial paralysis and scrotal tongue is known as Melkersson – Rosenthal syndrome.
HISTOLOGIC FEATURES
There is a focal noncasseating granuloma formation. It has many epitheloid cells and Langhans type of giant cells.
The vascular channels are surrounded by an inflammatory infiltrate consisting of lymphocytes plasma cells and histiocytes.
TREATMENT
No definitive treatment.
Previous Topic Developmental Anomalies : Cheilitis Glandularis
Next Topic Developmental Anomalies :Peutz Jhegers Syndrome

Developmental Anomalies : Cheilitis Glandularis; Etiology Clinical Features Oral Manifestations and Treatment

CLINICAL FEATURES
The opening of the accessory salivary glands on the lips become enlarged and appear as small red macules.
Enlargement of several salivary ducts lead\ to the enlargement of the lips.
Exudation of a dense fluid is found through the gland openings.
It has been classified into three types
1. Simple type
2. Superficial suppurative type also known as Bealz’s disease.
3. Deep suppurative type
The simple type is characterized by very tiny painless lesions.
The superficial suppurative type shows painless swelling, crustings and ulcerations apart from suppuration.
The deep suppurative type is painful, deep abscess formation.
HISTOLOGIC FEATURES
A diverse array of alterations are seen in the surface epithelium as well as the submucosal tissues.
The minor salivary glands may show features of nonspecific sialadenitis.
Atrophy or distention of acini, ductal ectasia with or without squamous metaplasia, chronic inflammatory infiltration, replacement of glandular parenchyma, and interstitial fibrosis may be seen.
Suppuration and sinus tracts in cases of bacterial infection.
Edema, hyperemia, hyperkeratosis, erosion and ulceration may also be seen.
TREATMENT
The lesion is treated surgically by stripping off the associated mucosa of the lip, or vermilionectomy.
Previous Topic Developmental Anomalies: Congenital Lip and Comissural Pits And Fistulas
Next Topic Developmental Anomalies : Cheilitis Granulomatosa