Latest About Herpese labialis, Blood Glucose And Magnifying Loupes

What Is The Role Of Gingival Blood Glucose In Prediction Of Diabetes ?

Gingival blood glucose was tested for its glucose content in patients reporting to an OPD. It was found that 40% of the patients who tested positive for the preliminary glucose test were actually having diabetes, when confirmed by other confirmatory lab diagnostic procedures.

What Gives Better Results - Microscope Or Magnifying Loupes ?

A 4 year retrospective study undertaken by Massimo revealed that the final outcomes of surgeries done under the magnification of a microscope or a magnifying loupe is same. The final result of both the type of magnification yields similar post operative results.

New Effective Treatment For Herpes Labialis

In vivo studies have confirmed the effectiveness of a new drug combination for the treatment of herpes labialis. Combining monocaprin with low doses of doxycycline has been proven to treat the herpes labialis infection, with much shorter recovery time. It is noteworthy that both the prodromal and active cases respond well to this new combination

How To Make A Dedicated Page For Reading Latest Journal Articles

Latest and current knowledge of research is of utmost importance to keep pace with the ever growing field of dentistry. One of the best methods to peacefully read journal articles without being disturbed by the distraction on the web is to make a dedicated page for the very same purpose.
It is a fairly simple process and one can make it with existing or new Gmail / Google id.
Steps:
1. Log in to iGoogle at www.igoogle.com with your existing gmail id.
Click on the page tab labeled "HOME" and you will see a dropdown list. At the bottom of this list see "add a tab" and click it. See Fig 1. below.

Fig 1: Adding a new tab in igoogle home.

 When you click this tab a box pops up. Fill the "tab name" to any sensible name you like, shorter the better. I have used OMR Journals. See Fig 2.

Fig 2: Adding the name of the journal page tab

 When you are done you will get a Message sating "Sorry............" But don't panic. Say thank you ! and click on the blue button labeled "Look for new stuff to add". See Fig 3.

Fig 3: The blue button to click despite the error message. 

 This will take you to a next page. Scroll a bit and see "Add a feed or gadget" and click. A new box pops up. Enter the RSS or Atom feed address of the journals you want to add.

Fig 4: Add a feed or gadget link when pressed give up a pop box.

 An violoa ! you have a tab with the latest headlines from the journal you wish. Clicking these headlines will take you to the actual journal article. If the journal give full length articles you can read the entire article at its earliest.

Fig 5: A new tab added from the journal Journal Of Rehabilitation. Similar more tabs can be added.

 The gadget is customizable, and you can choose how many head lines to display ranging from 1 to 9. The number of columns can also be customized in the settings tab. Keep adding more journal and stay ahead of the crowd - in fact ahead of even the intelligent crowd.

What is the cause of this central incisor notching?

What is the cause of this central incisor notching?
The patient is 32 years old male, presented with the chief complaint of sensitivity in anterior teeth.

Bilateral Central Incisor Notching

The story of this and similar cases is based on a very old tradition of Rajasthan, Uttar Pradesh And Some Areas of Bihar. Some people in these areas get their teeth tattooed with gold in various forms. Most common pattern is a triangle with three dots at each corner and apex at the superior end. Small round holes are drilled in the teeth with the help hand driven drills. The holes are placed at about 2 to 3 mm superior to the incisal edges. Gold is then filled in the prepared cavities.
In this patient, the teeth underwent severe attrition which lead to the expulsion of the tattoos and conversion of round holes into semicircles which appear as notches.
Finally the complete correct answer was given by Dr. Zulfiqar Hafeez (AMU) and a closest best was given by Dr. Anshul Gupta (JDC) and Dr. Kritika Roy (JDC).

Dramatic Appearance Of An Innocuous Gingival Lesion

The patient age 27 years male reported with the chief complaint of swelling and spontaneous bleeding from the lesion. Swelling started about 7 months back. Since then it is growing in size and shown increased tendency to bleed. No tenderness on palpation. Very soft in consistency. Profuse bleeding on palpation. Both the Maxillary Central Incisors have been RC treated about 3 years back.

The final diagnosis was Localized Inflammatory Gingival Hyperplasia

Post operative result at 14 days recall.

Treatment

The treatment instituted was oral prophylaxis with manual scaling instruments. The patient was advised to swish and gargle with warm saline water 3 times a day. Second prophylaxis was performed after 7 days. The results can be seen in the above picture.

Stem Cell Dentistry: Charismatic Regeneration

Stem cells are unspecialized cells which can renew themselves and give birth to various specialized cells (totipotent cells, pleuripotent cells, multipotent cells and progenitor cells) that constitute an embryo. They act as basic building blocks and have a potential to repair the damaged and regenerate new organs and tissues.


Stem cells of dental origin:
* Bone marrow stem cells
* Dentin pulp stem cells
* Periodontal ligament stem cells
* Cemetoblast like cells
* SHED(Stem cells of human exfoliated and deciduous teeth)
* Wisdom teeth

Major prospective uses of stem cells in dentistry:

Development of a new tooth
Primary teeth, wisdom tooth, jaw bones, periodontal ligament and pulp are used to regenerate an entire tooth, restore nerve cells damaged in Parkinson’s disease , correction of cleft palate and treatment of missing teeth replacing the removable dentures and implants. Eg -If a tooth is injured during an accident usually root canals are needed and the tooth dies, instead stem cell aided new pulp can be generated in a tooth.

Regenerative techniques for periodontal diseases
In the coming future, periodontium injectible gel will prove to be useful in the development of new periodontal tissues through guided tissue and bone regeneration techniques.
[Injectible gel is a mixture of ex-vivo cultured mesenchymal stem cells, ex-vivo cultured osteoblast like cells differentiated from mesenchymal stem cells and scaffold {human thrombin, platelet rich plasma and calcium chloride}]

Dentofacial orthopaedics
Mesenchymal stem cells provide a continuous supply of osteogenic cells (osteoblasts and chondroblasts) required for bone remodelling and fracture repair throughout adulthood. Therefore these cells play a significant role in the field of growth modification in orthodontics.


Fractures:
Especially delayed non union fractures.

Geno-dental interrelations:
Stem cells in the cervical loop of continuously growing mouse incisors shows that their maintenance and differentiation depends on genetic signal pathways (FGF –Fibroblast Growth Factor and Ectodysplastin)
They are used to correct defects caused by ectodermal dysplasia and cleidocranial dysplasia. 

About The Author:

Dr. Dipika Bumb; www.omrcafe.blogspot.com;
Contact email: drdipikabumb@gmail.com

Oral Submucous Fibrosis Recent Advances 2009

 In Vivo OSF Treatment Effectiveness Detection by Autofluorescence

Autofluorescence is the latest technique to assess the effectiveness of treatment in Oral Submucous Fibrosis (OSF). When tissues interact with light they emit back a light in minute quantities, known as autofluorescence. It can be detected with highly sensitive spectrophotometres. Normal mucosa shows emissions in different spectral range than the fibrosed mucosa. In cases that responded to the treatment showed emission spectrum similar to that of normal mucosa. The greatest advantage of this test is that it can be performed invivo , it is non invasive and does not show any related adverse effects.
Ref: Vedeswari CP, Jayachandran S, Ganesan S. In vivo autofluorescence characteristics of pre- and post-treated oral submucous fibrosis: A pilot study. Indian J Dent Res [serial online] 2009 [cited 2009 Dec 16];20:261-7. Available from: http://www.ijdr.in/text.asp?2009/20/3/261/57354

This Red Dye Writes About Oral Submucous Fibrosis In Greater Detail

Various dyes are used for staining sections of Oral Submucous Fibrosis (OSF). Picrosirius red stain under polarizing microscopy shows staining the finer fibres and correlation with clinicofunctional staging.
Ref: Ceena DE, Bastian TS, Ashok L, Annigeri RG. Comparative study of clinicofunctional staging of oral submucous fibrosis with qualitative analysis of collagen fibers under polarizing microscopy. Indian J Dent Res [serial online] 2009 [cited 2009 Dec 16];20:271-6. Available from: http://www.ijdr.in/text.asp?2009/20/3/271/57356

Efficacy Of Licopene In Management Of Oral Submucous Fibrosis

Background And Objective: OSMF is an avancing premalignant condition for which a reliable treatment modality has not yet evolved. The aim of the present study was to evaluate the efficacy of newer anti-oxidant - Lycopene in the treatment of OSMF.

Material And Methods: The study group included 50 patients with OSMF. The diagnosis of OSMF was established thrugh a composite of clinical and histopathologic characteristics. Out of 50 patients, 25 were given licopene (8 mg Lycored/ day in divided doses of 4 mg each for a period of 3 months. Remaining patients recieved placeo tablets twice a day. Patients were examined for changes in mouth opening and oter symptoms of OSMF during 3 months and were followed for the next 2 months.

Results: Lycopene was found to be significantly effeficaious in the amelioration of signs and symptoms of OSMF. It was also effective in reducing the objective signs of OSMF as demonstrated by the improved maximal mouth opening, ercentage of which was 69.56 (p<0.05).

Conclusion: Reactive oxygen compounds or free radicals have been implicated as one of the major harmful sector for premalignant and malignant conditions. Our study concludes that lycopene appears to be very promising drug in the management of OSMF.

Author Dr. Rajeev Sharma (standing left)

Co-Author Dr. Durgesh Bailoor (standing left)

The Effect Of Anti-Retroviral Therapy On The Prevalence Of Oral Manifestation In HIV Sero Positive Patients

Background & Objectives: Acquired immunodeficiency syndrome (AIDS) is a highly lethal, progressively epidemic viral infection characterized by profound impairment of the immune system. According to the Center for Disease Control and Prevention’s (CDC) new classification system, clinical AIDS is defined by a CD4 count of less than 200 (<200) and / or a CD4 percentage of less than 14. The main objective of the current study was to determine the prevalence of oral manifestation of HIV patients on Highly Active Antiretroviral Therapy (HAART) and to compare these with the prevalence of those who were not on (HAART) therapy.
 Methods: Patients were selected from the out patient department of P.M.N.M dental college and hospital Bagalkot and patients from NGOs centers working for HIV/AIDS, Karnataka. A cross sectional was conducted amongst 100 patients diagnosed as HIV sero positive. Information regarding, date of birth, CD4 cell count were obtained from the medical records. Oral examination was done using universal precautions recommended by (CDC). Findings were recorded by using internationally accepted presumptive clinical criteria. Chi-square statistical test were conducted to describe the relationship between the prevalence of Oral manifestation and HAART therapy
Results: The detection of oral manifestation was significantly decreased in subjects on HAART therapy (32%) compared to those who were not on HAART therapy (56%), (P<0.05).
Interpretation & Conclusion:  Compared to non-HAART group, subjects on HAART group had significantly fewer HIV related oral manifestations-probably as a result of an expression of their reconstituted immune system.
By: Dr. Neelkant Patil

What Does This Radiograph Reveal ?

A 37 year old, male patients reported to Department Of OMR, JDC, with the complaint of pain in back region of the jaw. History revealed that he did not use the affected side of the jaws for more than 4 years. It was clinically found that the pain is because of chronic pulpitis in his third molar. A radiograph was also taken.
The radiograph shows an extra radio-opaque mass attached to the distal surface of the crown of third molar.
The question here is to make the most probable diagnosis about the radiopaque mass.
Please write down your answers in the comments section.

Latest About HPV, HIV And Serum Cholesterol

Is HPV - 16 Responsile For Periodontal Breakdown ?

HPV - 16 is associated with a number of oral diseases for e.g. squamous cell carcinoma, condyloma acuminatum, verruca vulgaris, focal epithelial hyperplasia. Earlier it was hypothesised that it has a role in periodontal breakdown as well. A recent case control study by Verônica V. Horewicz et al.  found that HPV - 16 has no role in periodontal breakdown and periodontal tissues are not the reservoirs of HPV - 16 in the population examined.

Relation Between Mode Of HIV Transmission And Probability Of Oral Lesions

Journal of Oral Pathology and Medicine reports that the mode of HIV transmission is related to the probability of Oral Lesions. Two groups one with heterosexual HIV patients and the other with IV Drug abuser HIV patiens were seleced for the study. The examination revealed that the chances of oral lesions in heterosexual HIV patients is 75% while those in IV Drug Abusers is 46%. Along with this it was also found that candidiasis was the most common lesion affecting the oral cavity of HIV patients.

Serum Cholesterol Level And Oral Carcinoma

Serum cholesterol level is used in various anlysis to predict various diseases. In a study by Vidya K. Lohe published in Journal of Oral Pathology and Medicine it was found that oral carcinoma is associated with low total cholesterol, HDL And LDL, while oral precancers were associated with low total cholesterol and HDL.

By: Dr. Hamid Raihan
Jaipur Dental College
Jaipur.